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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49afaf41a9a737fbe5bccac837f21ca2884961c07e9cfd5a5e4a060150fa3db' 
  AND token = 'VpESJcDacQI0J0P55mtRMoJ+RznDIvVOs5t4HP4T0uA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}