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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49783b7aa0233364e25fb06c373c2f087249cce42f6651c874d60ec288ccdbf6' 
  AND token = 'mtQoImGczC08Pp1G4tf2ua6FRpV7qxZMMCQnt05um3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}