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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '997a4697608c61a93573775d651b76d69cef9e54d17d0236e9c2e6c4e59b5cce' 
  AND token = 'U0I7oh5SvVgbj8mhJOz5pv9lgU9qzArp5ruW1GHuDhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}