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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493d97477349ed9a7d391e785fb0d97e6b39450fa076c3fc355073de3fee597e' 
  AND token = 'b1ycvbX6ggtRAL0KC+IlkdmtfbG1jcwLH0NnAdWP4ZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}