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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291d84887365b527c09d0b70cc0be6a5032588c54bf925b3d2eb8a48deec8b33' 
  AND token = 'odeApzXv2nk9t6gcTt02G/87+U+SyML7ez77q0pqW5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}