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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41e50b1a3d1e13f12fd7b92980562dcd6bd1a4b0676001c4b482fa8e00e3bfcd' 
  AND token = '65UUSYNLRGjy2oVS8NoH7lG2fiy1od0GpwShxgg1030=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}