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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd9be8020738ed138a418d061a1f6766b42afa58624b365c3c641e0b8ff480d3' 
  AND token = 'Xf2Hc1E0q7euRUoCu/0GQi2dFLa3QOBTNCBEsSQpoJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}