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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa4c14f412675c29b86221f802f8df0ac144820b44c89a3a186e86f60cf8876d' 
  AND token = '273UzDZEDyW+0jqEPMufReiECqJt91tIt6tOAOrdrUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}