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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f4facb2bead36bca3eaa23a684f84161189e19a70ce714b1106fbf0a26a05f4' 
  AND token = 'I/LTV5NCaaNoWzJY92gdMcsD9aa6qAQj0gcxhWJaPQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}