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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '108322689f2fe4d95a59fc4563cd7d7d17017900a8497c5a2e95282da7e62c4c' 
  AND token = 'VSD4c7pE6Pij+q81icfZi5wvjAPGni4JNnIa2Nf6nAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}