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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3571b6216775bc82c3197064ef1f582669e5559da252014c81a54b3bf27b5a54' 
  AND token = 'z5FUHp+Cuim0HN+JgN6wcLbBFvgRrTV5i/yHX6k0FcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}