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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4598c80a047e562481ddd68308cf24d4d28db7eb5d40a333e6e87e16ba7e32f0' 
  AND token = 'Mum8B0pljntgd/OB1TA3pZaA+AYxK3Ks1tv4eLmbeCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}