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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd3fe5a9b3b794793978bd9145ccdc5f110b7627cb55a104a3a6a473b8ce333a' 
  AND token = 'hyyAGUaXtfDA7+vhc02dXE5wI1iuAYNSLywS9Kx8emI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}