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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd89d522ce16d8fdb744cfa3c9a50137100d150ef50be48f978810bf1d3ec4560' 
  AND token = 'isCW3agqx6KOzIcpQrRkw4cQuldnzKaR9Lvzzhxizh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}