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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f10c161511cec3ea2410ced7da37e7404621fc8b3c4fd781c9d70f02188245a' 
  AND token = 'P3i6k5ZVrOd6IawLBH+w2/ilXtI+TD7P9KZtNl0BgIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}