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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4be1d4004c1f5271c76b0145412ee66d88b6dd823e26f653e8cc1f2548d0fbd4' 
  AND token = 'brWWMiDmXIU/IuHXYAcc3x369ZGH5ycZXxd7khnGQjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}