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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41be0eedd9a2032c9ff3edeb42838176406e15bba26d51e66a2f0798e983f89d' 
  AND token = '5DragM52mu/3SEDLBApUU8s4/0sSUnAL4dACaO360PY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}