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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0de7e40a92e6c9e3254640aea8321eb844b918d580be1c0b551271192a92342e' 
  AND token = '43qIRUj9hHvnEqs1cOOLJnT6G5qjRz1Pev9Wn/Jn76Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}