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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bddf2a2d4318e29fa3f3a57c16d715ea640b34a84c0409b61f1314c256e351' 
  AND token = 'R+DdtrcLRGoyxqSuegCQzBt+9a5NskTlURgLzlRa/88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}