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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '872d0f4f5bac81c3a00c3de67e9cd953a8d9e71c0496f4510af36c26cd4ff1ea' 
  AND token = 'joxtcEsiA95wHgpXWsJNh74KssTvaF3k83SxHAOTPUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}