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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b09c1b6e431166d7cb6a646b54b6f91ccf9ebf22ad4fe4a58f57893847e8031' 
  AND token = 'I12rBEeDI/tXHfrK+PvRzZhXGTSOWXe6O6BK4nmkhZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}