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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e3c024f21d120f7707e6ded6fd1bfd864e3fe255828a7d795867b95354f8da4' 
  AND token = 'NYRmDN9eLyFHol5dabtqOeQ0OY0a50CNEVJAs6GDTJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}