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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cb164223858129a4a7fda098ff0e6f4bcff1e909c2c21f6562eefbb69aec1a6' 
  AND token = 'p7vrbxIZ2EcXvqY4RP6D5vc7XKT8dtNjjF4EmjZcy/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}