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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49cedabd2d7c37d1cbfd89381681d5c120b38ff397fa0def0e41066b9f267410' 
  AND token = 'kcNxz3HB5e2JUOz6sI2eFHLD3ppQLS83oL6ZN7mXRgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}