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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad25f2fda6660271a1921d793f1b1d1b45e89e698542b76f296673c3cf5110f' 
  AND token = 'ZvPptnMEce80J5g5CXfi1A/pwyKtk5PeerfsLbjBHVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}