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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2444d911999928a5302b0e0adffdc38dd09b9b67afc6ede95df09e5a8417903' 
  AND token = 'DhIY5AJdAUTnv7vE7Thk6Kvy4Occ8GfYRzsujsae1Gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}