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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af9a59ce5d4cf0e1d59c1d7c4d4d50dedbc6219cf2421c239b6303df2e2b685c' 
  AND token = 'zs2yZ9LySYYPTzcyoJUjYsA62fGOkxSgO8C1IvBMM3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}