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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb82d2eb0f342206de0bb250afb5da65feb8f6d591545270dfdfa05fd56f9921' 
  AND token = 'Chls+LupV+iDwBlHVE9iFN6SY0Vjp1d6KC8p3t6z120=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}