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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1885317c4f76172e5bc71ffa983f53f2e2e71d7614da1201ba8e7f94c13ad6b' 
  AND token = 'IOUjLZ3dnGERzc+RNPjbEHdx04xMPE9JKsGIgtG13aU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}